Osteoporotic fractures of spine- Important facts.


An osteoporotic vertebral fracture, also known as fragility fracture increase the risk of death as compared to the general population. The risk of death is highest in the first year after a fracture. Increased mortality risk gradually reduces after first year but can last up to 5-7 years of fracture. If you suffer from a second fragility fracture, which occurs quite often, the period with an increased risk of death gets further prolonged.

Only one third of osteoporotic spine fractures come to clinical attention, which makes the matter worse. This also makes collecting exact numbers and complications difficult. Studies suggest that mortality after osteoporotic spine fractures is slightly less than those of hip fractures. An estimated 24% of hip fracture patients aged 50 and over die in the first year following their fracture. With an increase in life expectancy and ageing population, we need to increase the awareness levels towards osteoporosis which not only increases risk of death but also imposes severe lifestyle restrictions.

What are the symptoms of an Osteoporotic spine fracture?

Recent onset pain in back after an insignificant fall is the most common presentation. Patients may not even recall the fall or trauma. Some patients do not have pain and present with reduction in height and may even loose an inch of their height over a year before presenting. This happens after vertebral fractures at multiple levels. These fractures may also lead to a progressive stooping posture resulting from a kyphotic deformity of spine due to vertebral compression fractures.  Kyphosis is basically an abnormal forward angulation of the spine. A kyphotic deformity may lead to constant pain, difficulty in walking and activities of daily living. The forward angulation of spine in kyphosis reduces the internal space available for internal organs like lungs and stomach which makes it difficult to breathe and eat.


How is an Osteoporotic spine fracture diagnosed?

As previously mentioned, a large proportion of patients may not be symptomatic. Having a high index of suspicion is the key, both from the perspective of a patient and a doctor This is where awareness programs come in.

A clinical examination may reveal spine tenderness, stooped posture, or weakness resulting from pinching of nerves. An x-ray and CT scan of spine will reveal the fracture and any abnormal alignment of the spine. CT scan is better at defining bony anatomy and extent of fractures.

MRI of the spine can help differentiate a recent fracture from an old silent fracture. MRI also shows whether the fracture is causing pressure on the nerves or not. DEXA scans or bone densitometry scans give an estimate of the degree of weakness, and are useful for comparing the effects of treatment during follow-up.

Vertebral fracture
A collapsed dorsal spine vertebra, and resulting abnormal forward angulation of spine.

What are the treatment options for Osteoporotic spine fractures?

Treatment varies upon the symptoms and degree of vertebral collapse. Patients with just pain are managed initially with rest and analgesics. Patients who fail to respond and have persistent pain after six weeks of conservative management, can be offered vertebral augmentation procedures. In Vertebroplasty, bone cement is injected into the vertebra through needles that are placed into the vertebral bodies under X-ray guidance.

In patients with vertebral height loss from a fracture, some height of individual vertebra can be restored using Kyphoplasty, in which a balloon is inflated inside the collapsed vertebra to augment height and then cement is injected. Vertebroplasty and Kyphoplasty have become quite popular because they offer good pain relief. Patients can resume normal activities after the procedure, thereby reducing the medical complications associated with bed rest in the elderly. Vertebroplasty and Kyphoplasty are quite safe procedures. Vertebroplasty does not require hospital admission and is done under local anesthesia or mild sedation, whereas Kyphoplasty requires a short hospital stay and general anesthesia for the procedure.

In patients with neurological deficits like leg weakness and kyphotic deformity, treatment may require complex procedure involving decompression of the nerves and internal stabilization with vertebral screws. These surgeries may be especially difficult with a high risk of an adverse outcome considering the elderly population at risk of these fractures.

How to prevent further Osteoporotic spine fractures?

Having Calcium and Vitamin D supplements are usually started, but may not help much in improving bone strength alone. Certain medications need to be started to prevent bones from weakening further by stopping the normal physiologic resorption and strengthening them by promoting re-mineralization. These therapies need to be monitored for their effects on bone strength and their side effects.

One needs to be in constant touch with a spine surgeon, physiotherapist and a physician after an osteoporotic fracture.

DisclaimerThis is for the general awareness of the patients and cannot replace expert medical advice. Patient treatments need to be individualised and that can be decided based on clinical examination and evaluation by a trained physician.

About the author: We thank Dr. Harnarayan Singh for his unconditional support and help in publishing this blog . Dr. Harnarayan Singh is a Neurosurgeon practising in Gurgaon with special interest in spine diseases.



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8 thoughts on “Osteoporotic fractures of spine- Important facts. 

  1. Postmenopausal women( not taking HRT),men above 70 years of age, any patients recieving prolonged oral steroids and those with past history of fragility fracture should get themselves evaluated for the risk of fresh fragility fracture by means of DXA scan and FRAX risk scores. Prevention of these fracture is of equal if not greater importance. An endocrinologist is the best person to advise on the medical management of osteoporosis in conjunction with the spine surgeon.

  2. Very good information regarding age related bone disease.
    Hope it will create the awareness so they can take preventive measures for such type of bone fracture.

  3. Very good information regarding age related bone disease.
    Hope it will create the awareness among the people so they can take preventive measures for such type of bone fracture.

  4. Wonderful description Dr Harnarayan. You have given a very clear picture of osteoporotic spine fracture.
    What are the latest advancement in the minimally invasive management of spine fracture ?

    1. Thank You.
      Vertebroplasty, Kyphoplasty, Cement augmented percutaneous spinal fixations are recent advances in management of such fractures, which are based on minimally invasive surgical principals. We will cover them in another blog.

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